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TRUTH IN PEPTIDES
Clinical DataResearch Only

Retatrutide Dosing Guide

Evidence-based dosing protocols across 1 administration approach.

Dosing Protocols

Phase 2 Obesity Trial

Clinical TrialSubcutaneous

Dose Range

112 mg

Frequency

weekly

Source

Phase 2 NEJM; TRIUMPH Phase 3 program

Escalation Schedule

Wk 1-4: 2 mg → Wk 5-8: 4 mg → Wk 9-12: 6 mg → Wk 13-16: 9 mg → Wk 17+: 12 mg

Triple GIP/GLP-1/glucagon agonist. 24.2% weight loss at 12 mg (48 wk). Not FDA-approved.

Administration

Delivery methods

Subcutaneous injection

Pending physician review — consult your provider before use.Updated 2026-04-10

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