Emerging tier · Weight Management
Sermorelin for Weight Management
A GHRH analog that stimulates natural growth hormone release from the pituitary gland.
Medical Disclaimer
Why Sermorelin for Weight Management
Role in Protocol
GH-mediated body composition improvement
Evidence Note
A GHRH analog that stimulates endogenous GH release. Some clinical data suggest favorable shifts in body composition (reduced fat mass, preserved lean mass), though evidence is less robust than for GLP-1 RAs.
Dosing Context
GH Optimization (Clinic Protocol)
Dose
200–500 mcg
Frequency
daily
Duration
3-6 months for full benefit
Often Used Alongside
Key Safety Notes
Active cancer or history of cancer
GH and IGF-1 are growth factors that may promote tumour growth.
Active pituitary tumours
GHRH stimulation may exacerbate pituitary pathology.
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