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Enclomiphene Dosing Guide

Evidence-based dosing protocols across 2 administration approaches.

Dosing Protocols

Secondary Hypogonadism

Clinical TrialOral

Dose Range

12.525 mg

Frequency

daily

Source

Wiehle et al. BJU Int 2013; PMID 23875626

Active isomer of clomiphene. Preserves spermatogenesis (unlike TRT). 25 mg → mean T 520 ng/dL at 14 d. Not FDA-approved (CRL 2020).

Lower Starting Dose

Off-Label ClinicOral

Dose Range

6.2512.5 mg

Frequency

daily

Some clinics start at 12.5 mg for borderline low T; 6.25 mg less commonly used.

Administration

Delivery methods

Oral capsule

Pending physician review — consult your provider before use.Updated 2026-04-10

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