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TRUTH IN PEPTIDES

Foundation tier · Anti-Aging & Longevity

Rapamycin for Anti-Aging & Longevity

Peer ReviewedFDA Approved

An mTOR inhibitor FDA-approved as an immunosuppressant, now studied for longevity applications.

Why Rapamycin for Anti-Aging & Longevity

Role in Protocol

mTOR inhibition for longevity

Evidence Note

The most robust longevity compound in preclinical research. The NIA Interventions Testing Program showed consistent lifespan extension in mice. Human data are limited to observational studies and small trials exploring intermittent low-dose protocols.

Literature Dosing

1-6 mg weekly oral -- ITP dosing data; human longevity dosing is investigational

Dosing Context

Longevity (Intermittent)

Dose

16 mg

Frequency

weekly

Transplant Immunosuppression (FDA-Approved)

Dose

215 mg

Frequency

daily

Full dosing guide →

Often Used Alongside

Key Safety Notes

Hypersensitivity to sirolimus or derivatives

Allergic reactions documented.

Active untreated infections

Immunosuppressive at transplant doses; even at low doses, immune function is modulated.

Severe hepatic impairment

Rapamycin is hepatically metabolised via CYP3A4.

Full safety profile →

Full Rapamycin Profile →

Full Anti-Aging & Longevity Protocol →